GPCRdb

CHEMBL593056

Agent/drug
Bioactivity

CHEMBL593056

SMILES	Cn1c(CN2CCC(c3ncc(C(F)(F)F)cc3Cl)CC2)nc2ccccc21
InChIKey	OTTSZTXIWXPOIL-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	3
Molecular weight (Da)	408.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pKi	6.10	6.10	6.10	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	5.80	5.80	5.80	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	5.60	5.60	5.60	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₂	GRM2	Human	Metabotropic glutamate	C	pEC50	6.20	6.80	7.40	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL593056

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.