CHEMBL75030


SMILES c1ccc2c(c1)CCCC2NC1=NCCO1
InChIKey FXNNPMSELIMMHU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 216.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 8.67 8.67 8.67 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.92 7.92 7.92 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.69 6.79 6.9 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 8.63 8.63 8.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 8.45 8.45 8.45 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 8.66 8.66 8.66 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 8.93 8.93 8.93 ChEMBL