GPCRdb

TERCONAZOLE

Agent/drug
Bioactivity

TERCONAZOLE

SMILES	CC(C)N1CCN(c2ccc(OC[C@H]3CO[C@](Cn4cncn4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1
InChIKey	BLSQLHNBWJLIBQ-OZXSUGGESA-N

Chemical Properties

Hydrogen bond acceptors	8
Hydrogen bond donors	0
Rotatable bonds	8
Molecular weight (Da)	531.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1A	ADA1A	Rat	Adrenoceptors	A	pKi	5.27	5.27	5.27	ChEMBL
α_1B	ADA1B	Rat	Adrenoceptors	A	pKi	5.10	5.10	5.10	ChEMBL
α_1B	ADA1B	Rat	Adrenoceptors	A	pKi	8.29	8.29	8.29	Drug Central
α_1D	ADA1D	Human	Adrenoceptors	A	pKi	5.15	5.15	5.15	ChEMBL
α_1D	ADA1D	Human	Adrenoceptors	A	pKi	8.28	8.28	8.28	Drug Central
α_2A	ADA2A	Human	Adrenoceptors	A	pKi	6.43	6.43	6.43	ChEMBL
α_2A	ADA2A	Human	Adrenoceptors	A	pKi	8.19	8.19	8.19	Drug Central
α_2B	ADA2B	Human	Adrenoceptors	A	pKi	5.90	5.90	5.90	ChEMBL
α_2B	ADA2B	Human	Adrenoceptors	A	pKi	8.23	8.23	8.23	Drug Central
α_2C	ADA2C	Human	Adrenoceptors	A	pKi	7.21	7.21	7.21	ChEMBL
α_2C	ADA2C	Human	Adrenoceptors	A	pKi	8.14	8.14	8.14	Drug Central
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pKi	4.39	4.39	4.39	ChEMBL
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pKi	8.36	8.36	8.36	Drug Central
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	5.63	5.63	5.63	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	8.25	8.25	8.25	Drug Central
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	5.44	5.44	5.44	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	8.26	8.26	8.26	Drug Central
5-HT₄	5HT4R	Guinea pig	5-Hydroxytryptamine	A	pKi	8.25	8.25	8.25	Drug Central
D₁	DRD1	Human	Dopamine	A	pKi	4.89	4.89	4.89	ChEMBL
D₁	DRD1	Human	Dopamine	A	pKi	8.31	8.31	8.31	Drug Central

Showing 1 to 20 of 32 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1A	ADA1A	Rat	Adrenoceptors	A	pIC50	4.88	4.88	4.88	ChEMBL
α_1A	ADA1A	Rat	Adrenoceptors	A	pIC50	8.31	8.31	8.31	Drug Central
α_1B	ADA1B	Rat	Adrenoceptors	A	pIC50	4.84	4.84	4.84	ChEMBL
α_1D	ADA1D	Human	Adrenoceptors	A	pIC50	4.84	4.84	4.84	ChEMBL
α_2A	ADA2A	Human	Adrenoceptors	A	pIC50	6.01	6.01	6.01	ChEMBL
α_2B	ADA2B	Human	Adrenoceptors	A	pIC50	5.56	5.56	5.56	ChEMBL
α_2C	ADA2C	Human	Adrenoceptors	A	pIC50	6.38	6.38	6.38	ChEMBL
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pIC50	4.05	4.05	4.05	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pIC50	5.09	5.09	5.09	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pIC50	5.16	5.16	5.16	ChEMBL
D₁	DRD1	Human	Dopamine	A	pIC50	4.59	4.59	4.59	ChEMBL
D₃	DRD3	Human	Dopamine	A	pIC50	5.33	5.33	5.33	ChEMBL
M₁	ACM1	Human	Acetylcholine (muscarinic)	A	pIC50	5.24	5.24	5.24	ChEMBL
M₂	ACM2	Human	Acetylcholine (muscarinic)	A	pIC50	4.89	4.89	4.89	ChEMBL
M₃	ACM3	Human	Acetylcholine (muscarinic)	A	pIC50	4.84	4.84	4.84	ChEMBL
M₄	ACM4	Human	Acetylcholine (muscarinic)	A	pIC50	4.86	4.86	4.86	ChEMBL
M₅	ACM5	Human	Acetylcholine (muscarinic)	A	pIC50	5.36	5.36	5.36	ChEMBL

Showing 1 to 17 of 17 entries

TERCONAZOLE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.