GPCRdb

OXYCODONE

Agent/drug
Bioactivity

OXYCODONE

SMILES	COc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(O)[C@@H](C2)N(C)CC[C@]314
InChIKey	BRUQQQPBMZOVGD-XFKAJCMBSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	1
Rotatable bonds	1
Molecular weight (Da)	315.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Rat	Opioid	A	pKi	8.22	8.22	8.220	Drug Central
κ	OPRK	Rat	Opioid	A	pKi	5.58	5.58	5.580	ChEMBL
κ	OPRK	Guinea pig	Opioid	A	pKi	6.49	6.49	6.490	ChEMBL
κ	OPRK	Rat	Opioid	A	pKi	8.25	8.25	8.250	Drug Central
κ	OPRK	Guinea pig	Opioid	A	pKi	8.19	8.19	8.190	Drug Central
μ	OPRM	Rat	Opioid	A	pKi	7.36	7.71	8.050	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	6.88	7.66	7.920	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	8.11	8.11	8.110	Drug Central
μ	OPRM	Rat	Opioid	A	pKi	8.13	8.13	8.130	Drug Central

Showing 1 to 9 of 9 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pEC50	5.4	5.4	5.400	ChEMBL
δ	OPRD	Human	Opioid	A	pEC50	8.27	8.27	8.270	Drug Central
κ	OPRK	Mouse	Opioid	A	pEC50	4.8	4.8	4.800	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	4.8	4.8	4.800	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	8.32	8.32	8.320	Drug Central
κ	OPRK	Mouse	Opioid	A	pEC50	8.32	8.32	8.320	Drug Central
μ	OPRM	Mouse	Opioid	A	pEC50	6.8	6.8	6.800	ChEMBL
μ	OPRM	Rat	Opioid	A	pEC50	7.6	7.6	7.600	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	6.3	7.19	7.770	ChEMBL
μ	OPRM	Mouse	Opioid	A	pEC50	8.17	8.17	8.170	Drug Central

Showing 1 to 10 of 10 entries

OXYCODONE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.