TRIFLUPROMAZINE


SMILES CN(C)CCCN1c2ccccc2Sc2ccc(C(F)(F)F)cc21
InChIKey XSCGXQMFQXDFCW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 352.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 8.55 8.55 8.55 PDSP Ki database
H1 HRH1 Rat Histamine A pKi 7.28 7.28 7.28 PDSP Ki database
D1 DRD1 Bovine Dopamine A pKi 6.28 6.28 6.28 PDSP Ki database
D2 DRD2 Bovine Dopamine A pKi 8.68 8.68 8.68 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.4 8.4 8.4 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.08 8.08 8.08 Drug Central
D2 DRD2 Human Dopamine A pKi 8.07 8.07 8.07 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 6.0 6.4 6.8 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.4 4.4 4.4 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 4.9 4.9 4.9 ChEMBL