GPCRdb

ATOMOXETINE

Agent/drug
Bioactivity

ATOMOXETINE

SMILES	CNCC[C@@H](Oc1ccccc1C)c1ccccc1
InChIKey	VHGCDTVCOLNTBX-QGZVFWFLSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	1
Rotatable bonds	6
Molecular weight (Da)	255.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1B	ADA1B	Rat	Adrenoceptors	A	pKi	6.00	6.00	6.00	PDSP Ki database
α_1D	ADA1D	Rat	Adrenoceptors	A	pKi	6.00	6.00	6.00	PDSP Ki database
α_2A	ADA2A	Human	Adrenoceptors	A	pKi	6.00	6.00	6.00	PDSP Ki database
α_2B	ADA2B	Mouse	Adrenoceptors	A	pKi	6.00	6.00	6.00	PDSP Ki database
β₁	ADRB1	Rat	Adrenoceptors	A	pKi	6.00	6.00	6.00	PDSP Ki database
β₂	ADRB2	Rat	Adrenoceptors	A	pKi	6.00	6.00	6.00	PDSP Ki database
δ	OPRD	Rat	Opioid	A	pKi	6.00	6.00	6.00	PDSP Ki database
κ	OPRK	Guinea pig	Opioid	A	pKi	6.00	6.00	6.00	PDSP Ki database
μ	OPRM	Rat	Opioid	A	pKi	6.00	6.00	6.00	PDSP Ki database
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	5.00	5.50	6.00	PDSP Ki database
5-HT_1B	5HT1B	Human	5-Hydroxytryptamine	A	pKi	6.00	6.00	6.00	PDSP Ki database
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	6.00	6.00	6.00	PDSP Ki database
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	6.00	6.00	6.00	PDSP Ki database
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	6.00	6.00	6.00	PDSP Ki database
5-HT₄	5HT4R	Guinea pig	5-Hydroxytryptamine	A	pKi	6.00	6.00	6.00	PDSP Ki database
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	6.00	6.00	6.00	PDSP Ki database
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pKi	6.00	6.00	6.00	PDSP Ki database
A₁	AA1R	Rat	Adenosine	A	pKi	6.00	6.00	6.00	PDSP Ki database
CCK₂	GASR	Mouse	Cholecystokinin	A	pKi	6.00	6.00	6.00	PDSP Ki database
D₁	DRD1	Rat	Dopamine	A	pKi	6.00	6.00	6.00	PDSP Ki database

Showing 1 to 20 of 30 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

TSH	TSHR	Human	Glycoprotein hormone	A	Potency	4.50	4.50	4.50	ChEMBL

Showing 1 to 1 of 1 entry

ATOMOXETINE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.