GPCRdb

CHEMBL64553

Agent/drug
Bioactivity

CHEMBL64553

SMILES	Oc1ccc2c(c1)O[C@@H](CNCc1ccccc1)CC2
InChIKey	DWUAAOIZQFTYQP-MRXNPFEDSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	2
Rotatable bonds	4
Molecular weight (Da)	269.1

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	7.65	7.65	7.65	ChEMBL
D₁	DRD1	Human	Dopamine	A	pKi	5.14	5.17	5.21	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pKi	8.48	9.17	9.80	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	6.13	7.64	8.91	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.50	8.58	8.62	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	6.94	7.33	7.93	ChEMBL
D₅	DRD5	Human	Dopamine	A	pKi	5.42	5.42	5.43	ChEMBL

Showing 1 to 7 of 7 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	10.70	10.70	10.70	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL64553

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.