GPCRdb

iodoproxyfan

Agent/drug
Bioactivity

iodoproxyfan

SMILES	Ic1ccc(COCCCc2cnc[nH]2)cc1
InChIKey	DCQNAFOCXVCDLB-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	1
Rotatable bonds	6
Molecular weight (Da)	342.0

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Human	Histamine	A	pKi	10.00	10.00	10.00	Guide to Pharmacology
H₃	HRH3	Rat	Histamine	A	pKi	9.60	9.60	9.60	Guide to Pharmacology
H₃	HRH3	Guinea pig	Histamine	A	pKd	8.30	8.30	8.30	ChEMBL
H₃	HRH3	Rat	Histamine	A	pKi	7.15	8.45	9.52	ChEMBL
H₃	HRH3	Human	Histamine	A	pKi	7.39	8.60	9.20	ChEMBL
H₃	HRH3	Rat	Histamine	A	pKi	8.30	9.02	9.70	PDSP Ki database
H₃	HRH3	Human	Histamine	A	pKi	9.20	9.20	9.20	PDSP Ki database
H₄	HRH4	Human	Histamine	A	pKi	7.90	7.90	7.90	ChEMBL
H₄	HRH4	Human	Histamine	A	pKi	7.90	7.90	7.90	PDSP Ki database

Showing 1 to 9 of 9 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Human	Histamine	A	pEC50	10.30	10.30	10.30	ChEMBL
H₄	HRH4	Human	Histamine	A	pEC50	7.90	7.90	7.90	ChEMBL

Showing 1 to 2 of 2 entries

iodoproxyfan

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.