GPCRdb

BACLOFEN

Agent/drug
Bioactivity

BACLOFEN

SMILES	NCC(CC(=O)O)c1ccc(Cl)cc1
InChIKey	KPYSYYIEGFHWSV-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	4
Molecular weight (Da)	213.1

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

No bioactivity data available.

BACLOFEN

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 8

Phase II 10

Phase III 8

Approved Yes

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease				Phase

Gene	Protein	Receptor family	Ligand type	Class	Indication name	ICD11	ATC	Association score	Phase	Approved

GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Alcohol dependence, unspecified	6C40.2Z		0.572	3	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Alcohol withdrawal, unspecified	6C40.4Z		0.496	3	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Autism spectrum disorder, unspecified	6A02.Z		0.161	1	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Cannabis dependence, unspecified	6C41.2Z		0.092	2	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Cerebral palsy, unspecified	8D2Z		0.540	4	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Cocaine dependence, unspecified	6C45.2Z		0.101	2	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Cramp or spasm	MB47.3		0.382	4	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	DNA repair defects other than combined T-cell or B-cell immunodeficiencies	4A01.31		0.018	1	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Gastro-oesophageal reflux disease, unspecified	DA22.Z		0.301	3	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Hepatocellular carcinoma of liver	2C12.02		0.077	2	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Hereditary sensory or autonomic neuropathy, unspecified	8C21.Z		0.259	3	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Injury of spinal cord, level unspecified	ND51.2		0.527	4	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Multiple sclerosis, unspecified	8A40.Z		0.567	4	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Nicotine dependence, unspecified	6C4A.2Z		0.103	2	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Other specified structural developmental anomalies of the neurenteric canal, spinal cord or vertebral column	LA07.Y		0.370	4	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Pain, unspecified	MG3Z		0.519	2	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Unknown or unspecified psychoactive substance dependence, substance and state of remission unspecified	6C4G.2Z		0.390	1	Yes
GABR2	GABA_B2	GABA_B receptors	Amino acid receptors	Class C	Alcohol dependence, unspecified	6C40.2Z		0.567	3	Yes
GABR2	GABA_B2	GABA_B receptors	Amino acid receptors	Class C	Alcohol withdrawal, unspecified	6C40.4Z		0.495	3	Yes
GABR2	GABA_B2	GABA_B receptors	Amino acid receptors	Class C	Autism spectrum disorder, unspecified	6A02.Z		0.172	1	Yes

Showing 1 to 20 of 34 entries

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BACLOFEN

BACLOFEN

Chemical Properties

Database connections

No bioactivity data available.

BACLOFEN

Drug properties

Clinical Trials

Database connections

Sankey plot

Drug Information