CHEMBL594469


SMILES Fc1ccc(F)c(CO[C@H]2CCc3ccc(N4CCNCC4)nc32)c1
InChIKey PUSWEWCVDWRQPZ-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 345.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.82 6.82 6.82 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.6 7.6 7.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 5.57 5.57 5.57 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.85 8.85 8.85 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 5.82 5.82 5.82 ChEMBL