GPCRdb

CHEMBL7393

Agent/drug
Bioactivity

CHEMBL7393

SMILES	CCCN1CCC[C@H](c2cccc(O)c2)C1
InChIKey	HTSNFXAICLXZMA-ZDUSSCGKSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	1
Rotatable bonds	3
Molecular weight (Da)	219.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1B	ADA1B	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	PDSP Ki database
α_1D	ADA1D	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	PDSP Ki database
β₂	ADRB2	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	PDSP Ki database
δ	OPRD	Human	Opioid	A	pKi	5.00	5.00	5.00	PDSP Ki database
κ	OPRK	Human	Opioid	A	pKi	5.58	5.58	5.58	PDSP Ki database
μ	OPRM	Human	Opioid	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	6.06	6.06	6.06	PDSP Ki database
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_1E	5HT1E	Human	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_2C	5HT2C	Rat	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_5A	5HT5A	Human	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
CB₁	CNR1	Rat	Cannabinoid	A	pKi	5.00	5.00	5.00	PDSP Ki database
D₁	DRD1	Human	Dopamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
D₂	DRD2	Rat	Dopamine	A	pKi	6.72	6.72	6.72	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	5.67	6.06	6.46	PDSP Ki database
D₂	DRD2	Mouse	Dopamine	A	pKi	5.25	5.25	5.25	PDSP Ki database
D₃	DRD3	Rat	Dopamine	A	pKi	6.99	6.99	6.99	PDSP Ki database
D₄	DRD4	Human	Dopamine	A	pKi	6.01	6.13	6.26	PDSP Ki database
D₅	DRD5	Human	Dopamine	A	pKi	5.00	5.00	5.00	PDSP Ki database

Showing 1 to 20 of 25 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Rat	Dopamine	A	pIC50	4.64	5.80	7.01	ChEMBL
M₁	ACM1	Rat	Acetylcholine (muscarinic)	A	Potency	4.55	4.78	5.00	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL7393

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.