CHEMBL119668


SMILES Fc1ccc(CCN2CCN(CCCc3c[nH]c4ccc(-n5cnnc5)cc34)CC2)cc1F
InChIKey SGMZXGQIMCPURW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 450.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 7.01 7.04 7.08 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pEC50 8.72 8.94 9.15 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 9.0 9.03 9.05 ChEMBL