GPCRdb

PERHEXILINE

Agent/drug
Bioactivity

PERHEXILINE

SMILES	C1CCC(C(CC2CCCCN2)C2CCCCC2)CC1
InChIKey	CYXKNKQEMFBLER-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	1
Hydrogen bond donors	1
Rotatable bonds	4
Molecular weight (Da)	277.3

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

M₁	ACM1	Human	Acetylcholine (muscarinic)	A	pKi	6.18	6.18	6.18	ChEMBL
M₁	ACM1	Human	Acetylcholine (muscarinic)	A	pKi	8.21	8.21	8.21	Drug Central
M₃	ACM3	Human	Acetylcholine (muscarinic)	A	pKi	6.18	6.18	6.18	ChEMBL
M₃	ACM3	Human	Acetylcholine (muscarinic)	A	pKi	8.21	8.21	8.21	Drug Central
M₄	ACM4	Human	Acetylcholine (muscarinic)	A	pKi	6.30	6.30	6.30	ChEMBL
M₄	ACM4	Human	Acetylcholine (muscarinic)	A	pKi	8.20	8.20	8.20	Drug Central
M₅	ACM5	Human	Acetylcholine (muscarinic)	A	pKi	6.11	6.11	6.11	ChEMBL
M₅	ACM5	Human	Acetylcholine (muscarinic)	A	pKi	8.21	8.21	8.21	Drug Central

Showing 1 to 8 of 8 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

GPR55	GPR55	Human	GPR18, GPR55 and GPR119	A	pIC50	5.50	5.50	5.50	ChEMBL
M₁	ACM1	Human	Acetylcholine (muscarinic)	A	pIC50	5.57	5.57	5.57	ChEMBL
M₃	ACM3	Human	Acetylcholine (muscarinic)	A	pIC50	5.51	5.51	5.51	ChEMBL
M₄	ACM4	Human	Acetylcholine (muscarinic)	A	pIC50	5.45	5.45	5.45	ChEMBL
M₅	ACM5	Human	Acetylcholine (muscarinic)	A	pIC50	5.96	5.96	5.96	ChEMBL
NPS	NPSR1	Human	Neuropeptide S	A	Potency	4.90	4.90	4.90	ChEMBL

Showing 1 to 6 of 6 entries

PERHEXILINE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.