CHEMBL2110365


SMILES CC[C@H](C)[C@H](N)C(=O)N[C@H]1CCC(=O)NC[C@@H](C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(N)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)[C@@H](C)CC)CCC(=O)NC[C@@H](C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(N)=O)NC(=O)[C@@H]2CCCN2C1=O
InChIKey RJRBRCCJETZJLT-FDYNHNOGSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y4 NPY4R Human Neuropeptide Y A pKi 7.05 8.32 9.59 ChEMBL
Y5 NPY5R Human Neuropeptide Y A pKi 6.94 6.94 6.94 ChEMBL
Y2 NPY2R Human Neuropeptide Y A pKi 7.26 7.26 7.26 ChEMBL
Y1 NPY1R Human Neuropeptide Y A pKi 8.99 9.57 10.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y4 NPY4R Human Neuropeptide Y A pEC50 7.43 8.02 8.6 ChEMBL
Y5 NPY5R Human Neuropeptide Y A pEC50 5.69 5.69 5.69 ChEMBL
Y2 NPY2R Human Neuropeptide Y A pEC50 6.01 6.01 6.01 ChEMBL