GPCRdb

CHEMBL78838

Agent/drug
Bioactivity

CHEMBL78838

SMILES	c1cncc(Cc2c[nH]cn2)c1
InChIKey	IQMRECYOUIKYGG-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	1
Rotatable bonds	2
Molecular weight (Da)	159.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Human	Histamine	A	pKi	7.12	7.20	7.28	ChEMBL
H₄	HRH4	Human	Histamine	A	pKi	6.16	6.58	7.00	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Human	Histamine	A	pEC50	6.85	7.13	7.41	ChEMBL
H₄	HRH4	Human	Histamine	A	pEC50	4.82	4.82	4.82	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL78838

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.