CHEMBL605405


SMILES Cc1ccc2c(c1)c1c(n2/C=C\c2ccccc2)CCN(C)C1
InChIKey XQDRWCFJBHLWPR-RAXLEYEMSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 302.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 8.85 8.85 8.85 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 9.62 9.62 9.62 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 9.32 9.32 9.32 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 9.21 9.21 9.21 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 9.68 9.68 9.68 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.46 7.46 7.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pIC50 6.81 6.98 7.16 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.06 7.06 7.06 ChEMBL