CHEMBL606556


SMILES CN1CCC[C@@H]1Cc1c[nH]c2ccc(NS(=O)(=O)c3cccc(Cl)c3)cc12
InChIKey HJRBYTHOWGFPSH-QGZVFWFLSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 403.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.57 8.57 8.57 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 8.37 8.37 8.37 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.33 8.33 8.33 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.03 6.03 6.03 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.64 6.64 6.64 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 9.4 9.4 9.4 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.62 7.62 7.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pEC50 8.8 8.8 8.8 ChEMBL