CHEMBL266417


SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](C(N)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O
InChIKey GGYWLZFXFKFWKL-MYJAXEPASA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pKi 7.58 7.58 7.58 ChEMBL
MC3 MC3R Human Melanocortin A pKd 8.3 8.3 8.3 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.85 6.85 6.85 ChEMBL
MC4 MC4R Human Melanocortin A pKd 9.3 9.3 9.3 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pEC50 9.36 9.36 9.36 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 10.41 10.41 10.41 ChEMBL
MC1 MSHR Human Melanocortin A pEC50 10.44 10.44 10.44 ChEMBL
MC5 MC5R Human Melanocortin A pEC50 7.55 7.55 7.55 ChEMBL
MC3 MC3R Human Melanocortin A pIC50 8.48 8.48 8.48 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 8.55 8.55 8.55 ChEMBL
MC4 MC4R Human Melanocortin A pIC50 8.74 8.74 8.74 ChEMBL