GPCRdb

MICONAZOLE

Agent/drug
Bioactivity

MICONAZOLE

SMILES	Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1
InChIKey	BYBLEWFAAKGYCD-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	0
Rotatable bonds	6
Molecular weight (Da)	414.0

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1D	ADA1D	Human	Adrenoceptors	A	pKi	5.83	5.83	5.83	ChEMBL
α_1D	ADA1D	Human	Adrenoceptors	A	pKi	8.23	8.23	8.23	Drug Central
α_2A	ADA2A	Human	Adrenoceptors	A	pKi	5.83	5.83	5.83	ChEMBL
α_2A	ADA2A	Human	Adrenoceptors	A	pKi	8.23	8.23	8.23	Drug Central
α_2B	ADA2B	Human	Adrenoceptors	A	pKi	5.79	5.79	5.79	ChEMBL
α_2B	ADA2B	Human	Adrenoceptors	A	pKi	8.24	8.24	8.24	Drug Central
β₁	ADRB1	Human	Adrenoceptors	A	pKi	5.14	5.14	5.14	ChEMBL
β₁	ADRB1	Human	Adrenoceptors	A	pKi	8.29	8.29	8.29	Drug Central
β₃	ADRB3	Human	Adrenoceptors	A	pKi	5.39	5.39	5.39	ChEMBL
β₃	ADRB3	Human	Adrenoceptors	A	pKi	8.27	8.27	8.27	Drug Central
δ	OPRD	Human	Opioid	A	pKi	5.92	5.92	5.92	ChEMBL
δ	OPRD	Human	Opioid	A	pKi	8.23	8.23	8.23	Drug Central
κ	OPRK	Human	Opioid	A	pKi	5.58	5.58	5.58	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	8.25	8.25	8.25	Drug Central
μ	OPRM	Human	Opioid	A	pKi	5.61	5.61	5.61	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	8.25	8.25	8.25	Drug Central
5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	5.18	5.18	5.18	ChEMBL
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	8.29	8.29	8.29	Drug Central
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pKi	5.03	5.03	5.03	ChEMBL
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pKi	8.30	8.30	8.30	Drug Central

Showing 1 to 20 of 66 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1D	ADA1D	Human	Adrenoceptors	A	pIC50	5.52	5.52	5.52	ChEMBL
α_2A	ADA2A	Human	Adrenoceptors	A	pIC50	5.40	5.40	5.40	ChEMBL
α_2B	ADA2B	Human	Adrenoceptors	A	pIC50	5.44	5.44	5.44	ChEMBL
β₁	ADRB1	Human	Adrenoceptors	A	pIC50	4.90	4.90	4.90	ChEMBL
β₃	ADRB3	Human	Adrenoceptors	A	pIC50	5.26	5.26	5.26	ChEMBL
δ	OPRD	Human	Opioid	A	pIC50	5.47	5.47	5.47	ChEMBL
κ	OPRK	Human	Opioid	A	pIC50	5.18	5.18	5.18	ChEMBL
μ	OPRM	Human	Opioid	A	pIC50	5.22	5.22	5.22	ChEMBL
5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pIC50	4.94	4.94	4.94	ChEMBL
5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pIC50	8.31	8.31	8.31	Drug Central
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pIC50	4.69	4.69	4.69	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pIC50	5.41	5.41	5.41	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pIC50	5.26	5.26	5.26	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pIC50	5.28	5.28	5.28	ChEMBL
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pIC50	4.96	4.96	4.96	ChEMBL
A₁	AA1R	Human	Adenosine	A	pIC50	4.90	4.90	4.90	ChEMBL
A_2A	AA2AR	Human	Adenosine	A	pIC50	4.85	4.85	4.85	ChEMBL
A₃	AA3R	Human	Adenosine	A	pIC50	5.55	5.55	5.55	ChEMBL
AT₂	AGTR2	Human	Angiotensin	A	pIC50	4.62	4.62	4.62	ChEMBL
CB₁	CNR1	Human	Cannabinoid	A	pIC50	4.68	4.68	4.68	ChEMBL

Showing 1 to 20 of 36 entries

MICONAZOLE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.