GPCRdb

HOMOHISTAMINE

Agent/drug
Bioactivity

HOMOHISTAMINE

SMILES	NCCCc1c[nH]cn1
InChIKey	IHDFTEVCMVTMSP-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	3
Molecular weight (Da)	125.1

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Guinea pig	Histamine	A	pKd	5.90	5.90	5.90	ChEMBL
H₃	HRH3	Human	Histamine	A	pKi	7.03	7.21	7.31	ChEMBL
H₄	HRH4	Human	Histamine	A	pKi	7.50	7.50	7.50	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Human	Histamine	A	pEC50	7.37	7.38	7.40	ChEMBL
H₄	HRH4	Human	Histamine	A	pEC50	6.67	6.69	6.70	ChEMBL

Showing 1 to 2 of 2 entries

HOMOHISTAMINE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.