DELTORPHIN C


SMILES CC(C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)NCC(N)=O)C(C)C
InChIKey CJAORFIPPWIGPG-QXYJMILXSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pKi 5.7 5.7 5.7 ChEMBL
δ OPRD Mouse Opioid A pKi 9.1 9.1 9.1 ChEMBL
μ OPRM Rat Opioid A pKi 5.41 6.45 6.83 ChEMBL
δ OPRD Human Opioid A pKi 8.76 8.76 8.76 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pIC50 9.47 9.47 9.47 ChEMBL
δ OPRD Mouse Opioid A pIC50 9.07 9.49 9.96 ChEMBL
δ OPRD Mouse Opioid A pEC50 7.9 7.9 7.9 ChEMBL
μ OPRM Rat Opioid A pIC50 5.67 5.71 5.78 ChEMBL
δ OPRD Human Opioid A pIC50 6.38 7.63 8.89 ChEMBL
δ OPRD Human Opioid A pEC50 8.33 8.33 8.33 ChEMBL
κ OPRK Human Opioid A pIC50 5.13 5.13 5.13 ChEMBL
μ OPRM Human Opioid A pEC50 5.95 5.95 5.95 ChEMBL
μ OPRM Human Opioid A pIC50 6.65 6.65 6.65 ChEMBL