CHEMBL331325


SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChIKey PJAMNQXPYIKTPE-KRCBVYEFSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 6.31 6.31 6.31 ChEMBL
μ OPRM Rat Opioid A pKi 9.59 9.7 9.82 ChEMBL
δ OPRD Human Opioid A pKi 6.55 6.55 6.55 ChEMBL
κ OPRK Human Opioid A pKi 6.28 6.28 6.28 ChEMBL
μ OPRM Human Opioid A pKi 9.09 9.09 9.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pIC50 9.23 9.23 9.23 ChEMBL
μ OPRM Human Opioid A pEC50 8.78 9.39 10.0 ChEMBL