CHEMBL63167


SMILES FC1(Cc2ccccc2C(F)(F)F)CCN(CCCc2c[nH]c3ccc(-n4cnnc4)cc23)CC1
InChIKey QCGOFEMUVCYZKT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 485.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pEC50 6.54 6.54 6.54 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 7.85 7.85 7.85 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pEC50 9.7 9.7 9.7 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 9.52 9.52 9.52 ChEMBL