CHEMBL63432


SMILES Fc1cccc(CCN2CCN(CC(F)Cc3c[nH]c4ccc(-n5cnnc5)cc34)CC2)c1
InChIKey ZIULJQIKRKMJNZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 450.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 5.92 5.96 6.0 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pEC50 6.09 6.09 6.09 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pEC50 8.36 8.39 8.42 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 8.29 8.39 8.46 ChEMBL