GPCRdb

BISACODYL

Agent/drug
Bioactivity

BISACODYL

SMILES	CC(=O)Oc1ccc(C(c2ccc(OC(C)=O)cc2)c2ccccn2)cc1
InChIKey	KHOITXIGCFIULA-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	0
Rotatable bonds	5
Molecular weight (Da)	361.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

κ	OPRK	Human	Opioid	A	pKi	6.01	6.01	6.01	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	8.22	8.22	8.22	Drug Central

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

κ	OPRK	Human	Opioid	A	pIC50	5.61	5.61	5.61	ChEMBL
GPR55	GPR55	Human	GPR18, GPR55 and GPR119	A	pIC50	6.04	6.04	6.04	ChEMBL
TSH	TSHR	Human	Glycoprotein hormone	A	Potency	5.60	5.75	5.90	ChEMBL

Showing 1 to 3 of 3 entries

BISACODYL

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.