CHEMBL3577981


SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O
InChIKey MTKQTEXYJKPBQD-GNDHHEKASA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pKd 6.4 6.4 6.4 ChEMBL
MC3 MC3R Mouse Melanocortin A pKi 6.4 6.4 6.4 ChEMBL
MC3 MC3R Mouse Melanocortin A pKd 6.3 6.33 6.4 ChEMBL
MC4 MC4R Mouse Melanocortin A pKi 7.7 7.7 7.7 ChEMBL
MC4 MC4R Mouse Melanocortin A pKd 7.7 8.03 8.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pIC50 4.91 4.91 4.91 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 5.35 5.35 5.35 ChEMBL
MC1 MSHR Mouse Melanocortin A pIC50 5.05 5.05 5.05 ChEMBL
MC3 MC3R Mouse Melanocortin A pIC50 4.77 4.77 4.77 ChEMBL
MC4 MC4R Mouse Melanocortin A pIC50 7.16 7.16 7.16 ChEMBL
MC4 MC4R Human Melanocortin A pIC50 7.16 7.16 7.16 ChEMBL