CHEMBL64610


SMILES CN1C(=O)COc2cc(CCCCN3CCN(c4cccc(C(F)(F)F)c4)CC3)ccc21
InChIKey WPAUYUKWTZISQN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 447.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Bovine 5-Hydroxytryptamine A pIC50 6.21 6.21 6.21 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pIC50 7.52 7.52 7.52 ChEMBL
D2 DRD2 Bovine Dopamine A pIC50 8.1 8.1 8.1 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 6.55 6.55 6.55 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 6.1 6.1 6.1 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 9.22 9.22 9.22 ChEMBL