CHEMBL64845


SMILES Oc1nc2ccc(CCCCN3CCN(c4cccc(C(F)(F)F)c4)CC3)cc2s1
InChIKey VSWGAMIGTKHGDL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 435.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Bovine 5-Hydroxytryptamine A pIC50 6.24 6.24 6.24 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pIC50 7.35 7.35 7.35 ChEMBL
D2 DRD2 Bovine Dopamine A pIC50 7.24 7.24 7.24 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 6.4 6.4 6.4 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 4.96 4.96 4.96 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 7.37 7.37 7.37 ChEMBL