FENOFIBRATE


SMILES CC(C)OC(=O)C(C)(C)Oc1ccc(C(=O)c2ccc(Cl)cc2)cc1
InChIKey YMTINGFKWWXKFG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 360.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β3 ADRB3 Human Adrenoceptors A pKi 4.03 4.03 4.03 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.91 5.91 5.91 ChEMBL
D3 DRD3 Human Dopamine A pKi 4.33 4.33 4.33 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.22 6.22 6.22 ChEMBL
A3 AA3R Human Adenosine A pKi 5.49 5.49 5.49 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.23 8.23 8.23 Drug Central
β3 ADRB3 Human Adrenoceptors A pKi 8.39 8.39 8.39 Drug Central
D3 DRD3 Human Dopamine A pKi 8.36 8.36 8.36 Drug Central
A3 AA3R Human Adenosine A pKi 8.26 8.26 8.26 Drug Central
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.21 8.21 8.21 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 7.2 7.2 7.2 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 5.62 5.62 5.62 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 5.67 5.67 5.67 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 4.8 4.8 4.8 ChEMBL
A3 AA3R Human Adenosine A pIC50 5.24 5.24 5.24 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.8 4.85 4.9 ChEMBL