PASIREOTIDE



PASIREOTIDE


SMILES NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](c2ccccc2)NC(=O)[C@@H]2C[C@H](OC(=O)NCCN)CN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)NC1=O
InChIKey VMZMNAABQBOLAK-IXZCVAHUSA-N

Chemical Properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Database connections



Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

PASIREOTIDE


Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug No

Clinical Trials

Phase I 12
Phase II 72
Phase III 12
Approved Yes

Database connections



Sankey plot

Hepatocellular carcinoma of liver There is 4 stuff in this nodeHepatocellular carcinoma ofliverNeoplasms There is 76 stuff in this nodeNeoplasmsPasireotide There is 100 stuff in this nodePasireotideSST2 receptor There is 25 stuff in this nodeSST2 receptorCutaneous neuroendocrine carcinoma There is 4 stuff in this nodeCutaneous neuroendocrine carcinomaMalignant neoplasms of prostate, unspecified There is 4 stuff in this nodeMalignant neoplasms ofprostate, unspecifiedOther specified malignant neoplasms of unspecified primary sites There is 4 stuff in this nodeOther specified malignantneoplasms of unspecifiedprimary sitesOther specified benign neoplasm of endocrine glands There is 4 stuff in this nodeOther specified benignneoplasm of endocrineglandsAcromegaly or pituitary gigantism There is 4 stuff in this nodeAcromegaly or pituitarygigantismEndocrine, nutritional or metabolic diseases There is 16 stuff in this nodeEndocrine, nutritional ormetabolic diseasesDumping syndrome There is 4 stuff in this nodeDumping syndromeDiseases of the digestive system There is 4 stuff in this nodeDiseases of thedigestive systemSST5 receptor There is 25 stuff in this nodeSST5 receptorMeningiomas, unspecified There is 4 stuff in this nodeMeningiomas, unspecifiedSST1 receptor There is 25 stuff in this nodeSST1 receptorOther specified malignant neoplasms of thymus There is 4 stuff in this nodeOther specified malignantneoplasms of thymusBenign neoplasm of endocrine pancreas There is 4 stuff in this nodeBenign neoplasm ofendocrine pancreasSST3 receptor There is 25 stuff in this nodeSST3 receptorPlasma cell myeloma There is 4 stuff in this nodePlasma cell myelomaNeoplasms of haematopoietic or lymphoid tissues, unspecified There is 4 stuff in this nodeNeoplasms of haematopoieticor lymphoid tissues,unspecifiedOther specified malignant neoplasms of pancreas There is 4 stuff in this nodeOther specified malignantneoplasms of pancreasSmall cell carcinoma of bronchus or lung There is 4 stuff in this nodeSmall cell carcinomaof bronchus orlungUnspecified malignant epithelial neoplasm of bronchus or lung There is 4 stuff in this nodeUnspecified malignant epithelialneoplasm of bronchusor lungMalignant neoplasms of breast, unspecified There is 4 stuff in this nodeMalignant neoplasms ofbreast, unspecifiedAdenocarcinoma of prostate There is 4 stuff in this nodeAdenocarcinoma of prostateMedullary carcinoma of thyroid gland There is 4 stuff in this nodeMedullary carcinoma ofthyroid glandMalignant neoplasms of thyroid gland, unspecified There is 4 stuff in this nodeMalignant neoplasms ofthyroid gland, unspecifiedUnspecified malignant neoplasms of unspecified sites There is 4 stuff in this nodeUnspecified malignant neoplasmsof unspecified sitesDuctal carcinoma in situ of breast There is 4 stuff in this nodeDuctal carcinoma insitu of breastPituitary-dependent cushing disease There is 4 stuff in this nodePituitary-dependent cushing diseaseEctopic acth syndrome There is 4 stuff in this nodeEctopic acth syndromeCushing syndrome, unspecified There is 4 stuff in this nodeCushing syndrome, unspecifiedPain, unspecified There is 4 stuff in this nodePain, unspecifiedSymptoms, signs or clinical findings, not elsewhere classified There is 4 stuff in this nodeSymptoms, signs orclinical findings, notelsewhere classified


Drug Information

Target Disease Phase
Gene Protein Receptor family Ligand type Class Indication name ICD11 ATC Association score Phase Approved