D-GLUTAMATE
| SMILES | N[C@H](CCC(=O)O)C(=O)O |
| InChIKey | WHUUTDBJXJRKMK-GSVOUGTGSA-N |
Chemical properties
| Hydrogen bond acceptors | 3 |
| Hydrogen bond donors | 3 |
| Rotatable bonds | 4 |
| Molecular weight (Da) | 147.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu2 | GRM2 | Rat | Metabotropic glutamate | C | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
| mGlu2 | GRM2 | Human | Metabotropic glutamate | C | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
| mGlu3 | GRM3 | Human | Metabotropic glutamate | C | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
| mGlu6 | GRM6 | Rat | Metabotropic glutamate | C | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
| mGlu8 | GRM8 | Rat | Metabotropic glutamate | C | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu6 | GRM6 | Rat | Metabotropic glutamate | C | pEC50 | 4.7 | 4.7 | 4.7 | ChEMBL |
| mGlu4 | GRM4 | Rat | Metabotropic glutamate | C | pEC50 | 4.92 | 4.92 | 4.92 | ChEMBL |
| mGlu3 | GRM3 | Rat | Metabotropic glutamate | C | pEC50 | 5.05 | 5.05 | 5.05 | ChEMBL |
| mGlu1 | GRM1 | Rat | Metabotropic glutamate | C | pEC50 | 5.0 | 5.0 | 5.0 | ChEMBL |
| mGlu2 | GRM2 | Rat | Metabotropic glutamate | C | pEC50 | 5.4 | 5.4 | 5.4 | ChEMBL |
| M1 | ACM1 | Rat | Acetylcholine (muscarinic) | A | Potency | 5.35 | 5.35 | 5.35 | ChEMBL |
| mGlu5 | GRM5 | Rat | Metabotropic glutamate | C | pEC50 | 5.36 | 5.36 | 5.36 | ChEMBL |