CHEMBL76237


SMILES COc1ccc2c(c1)c(CCN(C)C)cn2S(=O)(=O)c1ccccc1
InChIKey AIJIQCBYMBZLJD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 358.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 5.6 5.6 5.6 ChEMBL
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 5.38 5.38 5.38 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 7.64 7.64 7.64 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.04 5.35 5.66 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.14 6.14 6.14 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.72 5.97 6.22 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.6 8.66 8.7 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKd 8.88 8.88 8.88 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.1 7.1 7.1 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.96 6.05 6.15 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.68 6.68 6.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database