TICLOPIDINE


SMILES Clc1ccccc1CN1CCc2sccc2C1
InChIKey PHWBOXQYWZNQIN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 263.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.86 6.86 6.86 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.77 6.77 6.77 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.84 6.84 6.84 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 8.16 8.16 8.16 Drug Central
α2B ADA2B Human Adrenoceptors A pKi 8.16 8.16 8.16 Drug Central
α2C ADA2C Human Adrenoceptors A pKi 8.17 8.17 8.17 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pIC50 6.52 6.52 6.52 ChEMBL
α2C ADA2C Human Adrenoceptors A pIC50 5.93 5.93 5.93 ChEMBL
α2A ADA2A Human Adrenoceptors A pIC50 6.42 6.42 6.42 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.6 4.6 4.6 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 4.9 4.9 4.9 ChEMBL