FANANSERIN


SMILES O=S1(=O)c2cccc3cccc(c23)N1CCCN1CCN(c2ccc(F)cc2)CC1
InChIKey VGIGHGMPMUCLIQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 425.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Guinea pig Histamine A pKi 7.6 7.6 7.6 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 7.42 7.42 7.42 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.54 8.54 8.54 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.16 7.16 7.16 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.43 10.08 10.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.75 6.75 6.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database