CHEMBL8642


SMILES COc1ccc(OC)c(CC(C)N)c1
InChIKey LATVFYDIBMDBSY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 195.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 6.83 6.83 6.83 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.28 5.98 6.68 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.95 5.95 5.95 PDSP Ki database
5-HT2C K7GSR7 Pig 5-Hydroxytryptamine A pKi 5.91 5.91 5.91 PDSP Ki database
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pKi 5.07 5.07 5.07 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.28 5.83 6.68 PDSP Ki database
5-HT2B F6QI78 Bovine 5-Hydroxytryptamine A pKi 5.17 5.17 5.17 PDSP Ki database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.98 5.98 5.98 PDSP Ki database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.98 6.98 6.98 PDSP Ki database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 PDSP Ki database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKi 6.02 6.02 6.02 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database