GR 63799X


SMILES C1C(C(C(C1=O)CCC=CCCC(=O)OC2=CC=C(C=C2)NC(=O)C3=CC=CC=C3)OCC(COC4=CC=CC=C4)O)O
InChIKey QQTQLHVRUZWVQZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 15
Molecular weight (Da) 587.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Mouse Prostanoid A pKi 8.72 8.72 8.72 PDSP Ki database
EP4 PE2R4 Mouse Prostanoid A pKi 6.32 6.32 6.32 PDSP Ki database
EP3 PE2R3 Bovine Prostanoid A pKi 7.96 8.03 8.1 PDSP Ki database
FP PF2R Bovine Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database