CHEMBL94984


SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc3ccccc23)CC1
InChIKey VCFMMDVFGUQTHR-HXUWFJFHSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 5.6 5.6 5.6 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.7 5.7 5.7 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.9 5.9 5.9 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.8 5.8 5.8 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.2 6.2 6.2 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.4 5.4 5.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database