GONADORELIN


SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O
InChIKey XLXSAKCOAKORKW-AQJXLSMYSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
LH LSHR Rat Glycoprotein hormone A pKi 8.9 8.9 8.9 ChEMBL
LH LSHR Rat Glycoprotein hormone A pKi 8.05 8.05 8.05 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pIC50 8.15 8.36 8.7 ChEMBL
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pIC50 8.0 8.0 8.0 ChEMBL
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pIC50 8.06 8.06 8.06 Drug Central
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pIC50 8.1 8.1 8.1 Drug Central