CHEMBL103817


SMILES CC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
InChIKey OHBCPCNJWIQQPW-SSNHPIBPSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC3 MC3R Mouse Melanocortin A pKd 6.04 6.29 6.53 ChEMBL
MC3 MC3R Mouse Melanocortin A pKi 6.53 6.53 6.53 ChEMBL
MC4 MC4R Mouse Melanocortin A pKd 8.09 8.09 8.09 ChEMBL
MC4 MC4R Human Melanocortin A pKd 7.82 7.82 7.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pEC50 7.46 7.46 7.46 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 6.78 6.89 7.01 ChEMBL
MC1 MSHR Mouse Melanocortin A pIC50 5.79 5.79 5.79 ChEMBL
MC3 MC3R Mouse Melanocortin A pIC50 5.84 5.84 5.84 ChEMBL
MC4 MC4R Mouse Melanocortin A pEC50 8.11 8.11 8.11 ChEMBL
MC4 MC4R Mouse Melanocortin A pIC50 7.58 7.58 7.58 ChEMBL