GPCRdb

CHEMBL5083607

Agent/drug
Bioactivity

CHEMBL5083607

SMILES	COc1ccccc1-c1cc(C2CCN(C)C2)ccc1Cl
InChIKey	MQLWANLDQKRYQY-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	None
Hydrogen bond donors	None
Rotatable bonds	None
Molecular weight (Da)

Database connections

ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	6.70	6.70	6.70	ChEMBL
5-HT_1B	5HT1B	Human	5-Hydroxytryptamine	A	pKi	7.92	7.92	7.92	ChEMBL
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	7.72	7.72	7.72	ChEMBL
5-HT_1E	5HT1E	Human	5-Hydroxytryptamine	A	pKi	5.39	5.39	5.39	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	5.92	5.92	5.92	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	6.77	6.77	6.77	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	6.04	6.04	6.04	ChEMBL
5-HT_5A	5HT5A	Human	5-Hydroxytryptamine	A	pKi	6.00	6.00	6.00	ChEMBL
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pKi	7.52	7.52	7.52	ChEMBL

Showing 1 to 9 of 9 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pEC50	6.19	6.22	6.25	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL5083607

Drug properties

Molecular type	Na
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.