GPCRdb

CHEMBL5085974

Agent/drug
Bioactivity

CHEMBL5085974

SMILES	CN(C)C(=O)C(CCN1CCN(c2cccc(Cl)c2Cl)CC1)(c1ccccc1)c1ccccc1
InChIKey	GCEDZTWELCPACO-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	None
Hydrogen bond donors	None
Rotatable bonds	None
Molecular weight (Da)

Database connections

ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

μ	OPRM	Human	Opioid	A	pKi	9.08	9.08	9.08	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	7.13	7.31	7.50	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	6.50	6.63	6.77	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	6.99	6.99	6.99	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

μ	OPRM	Human	Opioid	A	pEC50	6.58	7.19	7.91	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	6.13	6.13	6.13	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL5085974

Drug properties

Molecular type	Na
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.