CHEMBL428801


SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](C(N)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc2ccc(I)cc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O
InChIKey NVIBFTUPAARCBA-MYGWSCCLSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKd 10.3 10.3 10.3 ChEMBL
MC3 MC3R Human Melanocortin A pKd 8.3 8.3 8.3 ChEMBL
MC4 MC4R Human Melanocortin A pKd 9.7 9.7 9.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pEC50 9.16 9.16 9.16 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 9.72 9.72 9.72 ChEMBL
MC1 MSHR Human Melanocortin A pEC50 10.26 10.26 10.26 ChEMBL
MC3 MC3R Human Melanocortin A pIC50 8.74 8.74 8.74 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 8.95 8.95 8.95 ChEMBL
MC4 MC4R Human Melanocortin A pIC50 8.6 8.6 8.6 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 9.24 9.24 9.24 ChEMBL