CARBACHOL


SMILES C[N+](C)(C)CCOC(=O)N.[Cl-]
InChIKey AIXAANGOTKPUOY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 182.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.2 7.55 7.92 PDSP Ki database
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.0 6.9 8.89 PDSP Ki database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 5.81 6.96 8.12 PDSP Ki database
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 5.35 5.59 5.7 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 5.0 5.0 5.0 PDSP Ki database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.0 6.66 7.7 PDSP Ki database
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 5.0 5.0 5.0 PDSP Ki database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.37 8.37 8.37 PDSP Ki database
M1 ACM1 Mouse Acetylcholine (muscarinic) A pKi 8.11 8.11 8.11 Drug Central
M2 ACM2 Mouse Acetylcholine (muscarinic) A pKi 8.09 8.09 8.09 Drug Central
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 8.08 8.08 8.08 Drug Central
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 8.12 8.12 8.12 Drug Central
M4 ACM4 Rat Acetylcholine (muscarinic) A pKi 8.25 8.25 8.25 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Human Acetylcholine (muscarinic) A pEC50 8.07 8.07 8.07 Drug Central
M2 ACM2 Human Acetylcholine (muscarinic) A pEC50 8.1 8.1 8.1 Drug Central
M3 ACM3 Human Acetylcholine (muscarinic) A pEC50 8.06 8.06 8.06 Drug Central
M4 ACM4 Human Acetylcholine (muscarinic) A pEC50 8.12 8.12 8.12 Drug Central
M5 ACM5 Human Acetylcholine (muscarinic) A pEC50 8.09 8.09 8.09 Drug Central