ETICLOPRIDE,S(-)


SMILES CCC1=CC(=C(C(=C1O)C(=O)NCC2CCCN2CC)OC)Cl
InChIKey AADCDMQTJNYOSS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 340.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.57 7.61 7.65 PDSP Ki database
D2 DRD2 Rat Dopamine A pKi 8.8 9.73 10.7 PDSP Ki database
D4 DRD4 Rat Dopamine A pKi 7.19 7.19 7.19 PDSP Ki database
D1 DRD1 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 10.0 10.0 10.0 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.75 5.75 5.75 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 10.0 10.0 10.0 PDSP Ki database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 6.15 6.15 6.15 PDSP Ki database
D5 DRD5 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
H1 HRH1 Rat Histamine A pKi 5.0 5.0 5.0 PDSP Ki database
β2 ADRB2 Rat Adrenoceptors A pKi 5.0 5.0 5.0 PDSP Ki database
D2 DRD2 Dog Dopamine A pKi 10.05 10.05 10.05 PDSP Ki database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database