CARBACYCLIN


SMILES CCCCCC(C=CC1C(CC2C1CC(=CCCCC(=O)O)C2)O)O
InChIKey XZFRIPGNUQRGPI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight (Da) 350.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FP PF2R Mouse Prostanoid A pKi 5.92 5.92 5.92 PDSP Ki database
IP PI2R Mouse Prostanoid A pKi 6.96 7.37 7.78 PDSP Ki database
EP2 PE2R2 Mouse Prostanoid A pKi 5.8 5.8 5.8 PDSP Ki database
EP4 PE2R4 Mouse Prostanoid A pKi 5.64 5.64 5.64 PDSP Ki database
EP3 PE2R3 Bovine Prostanoid A pKi 5.27 5.29 5.31 PDSP Ki database
EP1 PE2R1 Human Prostanoid A pKi 7.64 7.64 7.64 PDSP Ki database
EP3 PE2R3 Human Prostanoid A pKi 7.85 7.85 7.85 PDSP Ki database
EP4 PE2R4 Human Prostanoid A pKi 6.03 6.24 6.45 PDSP Ki database
DP1 PD2R Human Prostanoid A pKi 6.88 6.88 6.88 PDSP Ki database
FP PF2R Human Prostanoid A pKi 6.37 6.37 6.37 PDSP Ki database
IP PI2R Human Prostanoid A pKi 6.56 7.17 7.78 PDSP Ki database
EP1 PE2R1 Human Prostanoid A pKi 8.32 8.32 8.32 Drug Central
EP4 PE2R4 Human Prostanoid A pKi 8.29 8.29 8.29 Drug Central
IP PI2R Human Prostanoid A pKi 8.11 8.11 8.11 Drug Central
EP3 PE2R3 Mouse Prostanoid A pKi 7.51 7.51 7.51 PDSP Ki database
FP PF2R Bovine Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
DP1 PD2R Rat Prostanoid A pKi 5.45 5.45 5.45 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database