CLOPROSTENOL


SMILES C1C(C(C(C1O)C=CC(COC2=CC(=CC=C2)Cl)O)CC=CCCCC(=O)O)O
InChIKey VJGGHXVGBSZVMZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 11
Molecular weight (Da) 424.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Bovine Prostanoid A pKi 7.04 7.04 7.05 PDSP Ki database
FP PF2R Bovine Prostanoid A pKi 7.51 7.51 7.51 PDSP Ki database
EP1 PE2R1 Human Prostanoid A pKi 6.09 6.09 6.09 PDSP Ki database
EP3 PE2R3 Human Prostanoid A pKi 8.36 8.36 8.36 PDSP Ki database
EP4 PE2R4 Human Prostanoid A pKi 5.0 5.02 5.04 PDSP Ki database
DP1 PD2R Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
FP PF2R Human Prostanoid A pKi 9.33 9.33 9.33 PDSP Ki database
IP PI2R Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database