Darifenacin


SMILES C1CN(CC1C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N)CCC4=CC5=C(C=C4)OCC5
InChIKey HXGBXQDTNZMWGS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 426.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.64 8.64 8.64 PDSP Ki database
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 8.7 8.81 8.92 PDSP Ki database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.26 8.26 8.26 PDSP Ki database
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.33 7.33 7.33 PDSP Ki database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.08 9.08 9.08 PDSP Ki database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.07 8.07 8.07 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database