Homatropine


SMILES CN1C2CCC1CC(C2)OC(=O)C(C3=CC=CC=C3)O.Br
InChIKey DWSGTFTVBLXELC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 355.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 6.78 6.78 6.78 PDSP Ki database
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 7.38 7.38 7.38 PDSP Ki database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.6 7.6 7.6 PDSP Ki database
M4 ACM4 Chicken Acetylcholine (muscarinic) A pKi 7.14 7.14 7.14 PDSP Ki database
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 7.23 7.23 7.23 PDSP Ki database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.13 8.13 8.13 Drug Central
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.15 8.15 8.15 Drug Central
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.11 8.11 8.11 Drug Central
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.1 8.1 8.1 Drug Central
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.13 8.13 8.13 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database