CHEMBL1221452


SMILES CN1CCN(c2cccc(N(Cc3ccccc3)S(=O)(=O)c3ccc4ccccc4c3)c2)CC1
InChIKey PVAHGORZNPASFQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 471.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 8.52 8.52 8.52 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.03 6.03 6.03 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 6.55 6.55 6.55 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 7.3 7.3 7.3 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 7.5 7.5 7.5 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.69 5.69 5.69 ChEMBL