2-(4'-Methylaminophenyl)Benzothiazole


SMILES CNC1=CC=C(C=C1)N=NC2=CC3=C(C=C2)N=CS3
InChIKey HYOWJSJJAVEHTC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 268.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 PDSP Ki database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.1 8.1 8.1 PDSP Ki database
D5 DRD5 Human Dopamine A pKi 7.89 7.89 7.89 PDSP Ki database
EP3 PE2R3 Human Prostanoid A pKi 8.7 8.7 8.7 PDSP Ki database
EP4 PE2R4 Human Prostanoid A pKi 7.92 7.92 7.92 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.43 7.43 7.43 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database